Category: Person


Welcome Fahimeh!

My name is Fahimeh Khorsand and I will be working as a researcher with Prof. Haug and Prof. Reuter on an early drug discovery project for COPD (norsk: KOLS) treatment. I am a biochemist and interested in protein biochemistry, enzymes and developing bioassays. I received my PhD degree in Biochemistry from University College Dublin in 2016 and my PhD thesis was about the application of enzymes in production of some pharmaceutically important intermediates.
I have been working at the University of Bergen since 2018, first  as a researcher in the Department of Biological sciences and later as a postdoc in the Department of Biomedicine and have been involved in collaborative projects (BIOTEK2021, RESPOND3, TILD) in the groups of Profs. Reuter, Haug and Brenk.  

, mars 26, 2023. Category: Person.

Hello from, and welcome to, Tuba!

Hi folks!

I am Tuba Iftikhar, a researcher in postdoctoral training with assoc, prof. Mali Husby Rosnes. I hail from the historically and agriculturally rich land of Gujrat, Pakistan. Following the conventional scientific path to extend my practical knowledge of chemistry, I moved to Germany for my doctoral studies in Prof. Kögerler’s research group at RWTH Aachen and Forschungszentrum Jülich which successfully led me to earn my Ph.D.

I worked as an experimental chemist to target the synthesis of organo-functionalized derivatives of heterometallic PolyOxoMetalates (POMs) for the investigation of their single-molecule magnetic (SMM) behavior and catalytic properties.

My Postdoctoral training is based on the Research Project ‘‘Recyclable Catalysts for Sustainable Polymers from CO2 and Bio-based Epoxides’’ ReCat4Polymer which is funded by the Trond Mohn Foundation and the University of Bergen. I would aim to focus on the development of recyclable catalysts for the production of sustainable polymers, where CO2 and bio-based epoxides will be used as raw materials. POMs are considered the key components for developing such suitable and recyclable catalysts.

, mars 7, 2023. Category: Person.

Meet and greet Valerie and Claudia!

We are students in the masters’s program in biomedical chemistry in Mainz, Germany, and are here as ERASMUS+ exchange students for the next four months. We will work on reasearch projects in the group of professor Bengt Erik Haug. Our projects focus on the synthesis of novel antibiotics and is part of a collaboration between the Haug group and the group of professor Ruth Brenk at the Department of Biomedicine at UiB. Claudia works on a project targeting the fatty acid synthesis of bacteria while Valerie works on riboswitch ligands.

, mars 3, 2023. Category: Person.

Say Welcome! to Leif

My name is Leif and I have recently finished my Master studies in inorganic chemistry at Heidelberg University, Germany. I applied low-valent iron complexes in homogeneous catalysis enabling access to conformationally constrained building blocks relevant to drug-development and medicinal chemistry.

My doctoral research is focused on developing novel transition metal catalysts for nitrogen activation in the research group of Prof. Vidar Jensen.  The catalyst design is guided by quantum chemical calculations to predict active catalysts which are then followed up on in the laboratory. The project is funded by the Norwegian Centre for Hydrogen Research – HyValue – where one of the foci lies on developing ammonia as a novel, environmentally friendly hydrogen-based energy carrier.

Say Welcome! to Ihtisham

I am Ihtisham Ul Haq. I am starting my new job as a researcher in the Dietzel group. My research will be the synthesis of metal-organic frameworks (MOFs) for the removal of heavy metals from solution. You can find me in Room 2049. I received my PhD degree in Chemical Engineering from Beijing Institute of Technology, China. My thesis research was the synthesis of MOFs and COFs for the removal of CO2, SO2, and VOCs and my thesis&I won the award of “best dissertation of the year” and “best international student of the year”. Before joining UiB, I worked in industry as R&D manager from 2020 to 2022.

New company KinSea spun out from research at the Department of Chemistry and partners

Founders: Professors Bengt Erik Haug, UiB, and Kine Østnes Hansen, Annette Bayer, Jeanette Hammer Andersen, and Espen Holst Hansen, all UiT Photo: KinSea

The road from research laboratory to actually founding a company with the aim to bring a new therapeutic agent to the market is exceedingly long and thorny, and we are very pleased to congratulate Bengt Erik and his collaborators in Tromsø with reaching this milestone with KinSea Lead Discovery AS!

The company, KinSea, is formed on the basis of a proprietary drug class developed by the founders and is based on a naturally occurring molecule isolated from a benthic animal taken from the Barents Sea. The molecules have potential as pan-mutant FLT3 kinase inhibitors for the treatment of acute myeloid leukemia (AML), including drug-resistant mutations that are traditionally difficult to treat.

The effect has been shown in an animal model for AML, and the founders have also shown that the drugs have superior properties compared to existing FLT3 inhibitors, including broad activity against drug-induced resistant FLT3 mutants, improved selectivity and high activity in vivo. KinSea will further develop the technology to a preclinical candidate that will be ready for advanced preclinical and clinical testing through license agreements with partners. The company also wants to utilize UiT’s collection of bioactive substances from marine organisms to gradually expand its portfolio within drug development to become a sustainable supplier of promising drug candidates based on discoveries in our northern sea areas.

KinSea have ambitions beyond the specific drug classes described above, and aim to establish a broad portfolio of drug development projects based on the partners» unique access to bioactive substances from the Arctic and expertise in drug development. Quoting Bengt Erik Haug, professor in the Bioresources and Pharmaceutical chemistry group at our department, and now also inventor, Gründer and research director at KinSea: We look forward to continuing our long-standing collaboration in marine bioprospecting and taking our FLT3 inhibitors further through the development process towards clinical testing.

The project has been developed in a collaboration between UiT Norges arktiske universitet, Universitetet I Bergen, and Lead Discovery Center GmbH through several projects funded by the Norwegian Research Council and the regional biotechnology program MABIT. KinSea is initially financed through a convertible loan from KHAN Technology Transfer Fund I GmbH & Co KG, a German venture fund with a focus on early-stage investments within drug development. The investor composition will be expanded in the time to come.

 

Minneord over Sverre Hauge

Sverre Hauge, tidligere førsteamanuensis (1965-2004) og instituttstyrer (1984-85) ved Kjemisk institutt, gikk bort 8. januar i år, vel 90 år gammel.

Da dr. tech. Olav Foss i 1956 etterfulgte professor Gaarder som styrer ved Kjemisk institutt, etablerte han raskt en forskningsgruppe innen uorganisk kjemi. Sverre Hauge var en av hans tidlige studenter som etter oppnådd embetseksamen i kjemi (cand. real. 1960), ble rekruttert som stipendiat og fra 1965 ansatt i fast vitenskapelig stilling, først som universitetslektor og fra 1971 som førsteamanuensis fram til aldersavgang i 2004.

Forskningen på Uorganisk avdeling var i hovedsak konsentrert om syntese, kjemiske egenskaper og struktur av svovel-, selen- og tellur-forbindelser, og Sverre spesialiserte seg på studier av selen-forbindelser. Hans dr. philos. avhandling fra 1978 har tittelen Linear three-selenium systems, reactions and crystal structures.

Fra siste del av 1980-tallet samarbeidet Sverre Hauge og hans nære kollega førsteamanuensis Kjartan Marøy om studier av kalkogen-halogen-forbindelser. En rekke nye salter av polymere kloro- og bromo-selenater ble syntetisert og isolert fra ikke-vandige løsningsmidler og karakterisert ved røntgenkrystallografiske metoder. I noen av forbindelsene forekommer selen i to oksidasjonstrinn, og figuren (under) viser et dianion med oktaedrisk-koordinert Se(IV) og kvadratisk-planart Se(II) atom, forbundet med to bromid-broer.

Da Kjemisk institutt ønsket å etablere aktivitet innen uorganisk analytisk kjemi, tok parhestene Hauge og Marøy, som begge var sentrale bidragsytere innen instituttets undervisning i analytisk kjemi, opp forskning og veiledning innen dette feltet. Prosjektet som varte en 10-årsperiode fra midt på 1980-tallet, omfattet utvikling av metoder for kvantitativ bestemmelse av fosfat, sulfat og halogenider ved molekylær emisjons-spektroskopi i flamme, bestemmelse av tungmetaller i vev, samt fjerning av fluorid fra brønnvann.  Én dr. scient.- og fire hovedfags-kandidater utførte sine forskningsprosjekter hos Sverre og Kjartan i denne tiden.

Som i våre dager, var andre halvdel av 60-tallet en tid for hektiske byggeplaner for realfagene ved UiB. Ved Kjemisk institutt la spesielt Sverre Hauge ned et stort arbeid med planlegging av forsknings- og undervisningslaboratorier, kontorer, og innredning. I 1971 kom første bevilgning til utgraving av tomt, bygging startet i august 1974, og i juni 1977 sto Realfagbygget klart. Kjemisk institutt kunne flytte inn i rommelige, moderne og hensiktsmessige lokaler, og Sverre høstet stor anerkjennelse for innsatsen som han la ned til fellesskapets beste!

Vi takker Sverre for en lang arbeidsdag og lyser fred over hans minne.

Tidligere og nåværende kollegaer ved Kjemisk institutt.

Meet our new Head of administration!

Hei KI!

Pål her, og i januar begynner jeg som administrasjonssjef på Kjemisk institutt. Jeg er innflytter fra Mandal med 20 års fartstid i Bergen, de fleste av dem har jeg vært tilknyttet UiB. Først som student på Humanistisk Fakultet, og så de siste åtte årene som ansatt ved MatNat. Jeg har jobbet i studieadministrasjonen på Geofysisk institutt, Institutt for fysikk og teknologi og nå sist som studieleder ved Institutt for informatikk. Gleder meg veldig til å ta fatt på ny jobb og til å bli kjent med dere alle sammen!

Hello KI!

I am Pål, and this January I will start my new position as Head of Administration at the Department of Chemistry. I am an “immigrant” from the southern-most city in Norway, Mandal, and have lived in Bergen for 20 years. The majority of these years have been with a connection to UiB, first as a student at the Faculty of Humanities, and then the last eight years as an employee at MatNat. I have worked in the study administration of Geophysical Institute, Department of Physics and Technology and finally as Head of Study Section at the Department of Informatics. Looking forward to embarking on my new position and to getting to know all of you!

Welcome Amrita!

Hello everyone! 

I am Amrita Panigrahi. I am an organic chemistry graduate from Bengaluru, India. I am starting my PhD research on frustrated Lewis pairs in metal-organic frameworks (MOFs) and their properties towards hydrogen and nitrogen activation in the Dietzel group. I have previously worked at Jubilant Biosys as a research associate in synthetic organic chemistry and analysis. You can find me in Room no. 2002, 2nd Floor.

Mali receives certification as holder of the prestigious TMS Starting Grant

TMS Starting Grant. Foto: Eivind Senneset, UiB

On the 1st of August 2022, Mali’s TMS Starting grant project, Recyclable Catalysts for Sustainable Polymers from CO2 and Bio-based Epoxides (ReCat4Polymer), officially started. On Friday the 23rd of September she officially received her TMS badge from the Trond Mohn Foundation. The event was the TMS alumni night at Tårnsalen at the University Museum. Our rector Margareth Hagen was also present to celebrate the three new grant holders, Mali from Chemistry, Suzette Flantua at the Department of Biological Sciences and Carina Strell at the Centre for Cancer Biomarkers (CCBIO).

The aim of the generous funds from the Trond Mohn Foundation and the University of Bergen is to build up a research group to study recyclable catalysts for the production of sustainable plastics, where CO2 will be used as one of the raw materials.

TMS Starting Grant. Foto: Eivind Senneset, UiB

Mali will develop efficient and fully recyclable catalysts for the sustainable production of modern materials without the use of fossil raw materials. The project focuses specifically on the development of recyclable catalysts for the production of sustainable polymers, where CO2 and bio-based epoxides will be used as raw materials. This will be an important contribution to the UN’s 12th sustainability goal; «Responsible consumption and production». The key to obtaining suitable and recyclable catalysts lies in introducing polyoxometalates (POMs). POMs are a special class of inorganic compounds that is one of Mali’s specialties from her PhD at the University of Glasgow, Scotland. PhD student Leah Kristen Rai is already in place at the institute.

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